diff --git a/Marlin/src/gcode/config/M218.cpp b/Marlin/src/gcode/config/M218.cpp
index 47910e074..6b291b548 100644
--- a/Marlin/src/gcode/config/M218.cpp
+++ b/Marlin/src/gcode/config/M218.cpp
@@ -22,7 +22,7 @@
 
 #include "../../inc/MarlinConfig.h"
 
-#if HOTENDS > 1
+#if HAS_HOTEND_OFFSET
 
 #include "../gcode.h"
 #include "../../module/motion.h"
@@ -37,7 +37,7 @@
  *   T<tool>
  *   X<xoffset>
  *   Y<yoffset>
- *   Z<zoffset> - Available with DUAL_X_CARRIAGE, SWITCHING_NOZZLE and PARKING_EXTRUDER
+ *   Z<zoffset>
  */
 void GcodeSuite::M218() {
   if (get_target_extruder_from_command() || target_extruder == 0) return;
@@ -51,13 +51,10 @@ void GcodeSuite::M218() {
     hotend_offset[Y_AXIS][target_extruder] = parser.value_linear_units();
     report = false;
   }
-
-  #if HAS_HOTEND_OFFSET_Z
-    if (parser.seenval('Z')) {
-      hotend_offset[Z_AXIS][target_extruder] = parser.value_linear_units();
-      report = false;
-    }
-  #endif
+  if (parser.seenval('Z')) {
+    hotend_offset[Z_AXIS][target_extruder] = parser.value_linear_units();
+    report = false;
+  }
 
   if (report) {
     SERIAL_ECHO_START();
@@ -67,10 +64,8 @@ void GcodeSuite::M218() {
       SERIAL_ECHO(hotend_offset[X_AXIS][e]);
       SERIAL_CHAR(',');
       SERIAL_ECHO(hotend_offset[Y_AXIS][e]);
-      #if HAS_HOTEND_OFFSET_Z
-        SERIAL_CHAR(',');
-        SERIAL_ECHO(hotend_offset[Z_AXIS][e]);
-      #endif
+      SERIAL_CHAR(',');
+      SERIAL_ECHO(hotend_offset[Z_AXIS][e]);
     }
     SERIAL_EOL();
   }
@@ -81,4 +76,4 @@ void GcodeSuite::M218() {
   #endif
 }
 
-#endif // HOTENDS > 1
+#endif // HAS_HOTEND_OFFSET
diff --git a/Marlin/src/gcode/feature/pause/M125.cpp b/Marlin/src/gcode/feature/pause/M125.cpp
index fbba475f2..714339246 100644
--- a/Marlin/src/gcode/feature/pause/M125.cpp
+++ b/Marlin/src/gcode/feature/pause/M125.cpp
@@ -65,7 +65,7 @@ void GcodeSuite::M125() {
   // Lift Z axis
   if (parser.seenval('Z')) park_point.z = parser.linearval('Z');
 
-  #if HOTENDS > 1 && DISABLED(DUAL_X_CARRIAGE) && DISABLED(DELTA)
+  #if HAS_HOTEND_OFFSET && DISABLED(DUAL_X_CARRIAGE) && DISABLED(DELTA)
     park_point.x += (active_extruder ? hotend_offset[X_AXIS][active_extruder] : 0);
     park_point.y += (active_extruder ? hotend_offset[Y_AXIS][active_extruder] : 0);
   #endif
diff --git a/Marlin/src/gcode/feature/pause/M600.cpp b/Marlin/src/gcode/feature/pause/M600.cpp
index be03c736c..42ed74dbe 100644
--- a/Marlin/src/gcode/feature/pause/M600.cpp
+++ b/Marlin/src/gcode/feature/pause/M600.cpp
@@ -87,7 +87,7 @@ void GcodeSuite::M600() {
   if (parser.seenval('X')) park_point.x = parser.linearval('X');
   if (parser.seenval('Y')) park_point.y = parser.linearval('Y');
 
-  #if HOTENDS > 1 && DISABLED(DUAL_X_CARRIAGE) && DISABLED(DELTA)
+  #if HAS_HOTEND_OFFSET && DISABLED(DUAL_X_CARRIAGE) && DISABLED(DELTA)
     park_point.x += (active_extruder ? hotend_offset[X_AXIS][active_extruder] : 0);
     park_point.y += (active_extruder ? hotend_offset[Y_AXIS][active_extruder] : 0);
   #endif
diff --git a/Marlin/src/inc/Conditionals_LCD.h b/Marlin/src/inc/Conditionals_LCD.h
index 608225ca4..0869faa8e 100644
--- a/Marlin/src/inc/Conditionals_LCD.h
+++ b/Marlin/src/inc/Conditionals_LCD.h
@@ -458,6 +458,8 @@
 
 #define DO_SWITCH_EXTRUDER (ENABLED(SWITCHING_EXTRUDER) && (DISABLED(SWITCHING_NOZZLE) || SWITCHING_EXTRUDER_SERVO_NR != SWITCHING_NOZZLE_SERVO_NR))
 
+#define HAS_HOTEND_OFFSET (HOTENDS > 1)
+
 /**
  * DISTINCT_E_FACTORS affects how some E factors are accessed
  */
diff --git a/Marlin/src/inc/Conditionals_post.h b/Marlin/src/inc/Conditionals_post.h
index 6cca5426d..f6345f3ec 100644
--- a/Marlin/src/inc/Conditionals_post.h
+++ b/Marlin/src/inc/Conditionals_post.h
@@ -413,7 +413,6 @@
 /**
  * Default hotend offsets, if not defined
  */
-#define HAS_HOTEND_OFFSET_Z (HOTENDS > 1 && (ENABLED(DUAL_X_CARRIAGE) || ENABLED(SWITCHING_NOZZLE) || ENABLED(PARKING_EXTRUDER)))
 #if HOTENDS > 1
   #ifndef HOTEND_OFFSET_X
     #define HOTEND_OFFSET_X { 0 } // X offsets for each extruder
@@ -421,8 +420,8 @@
   #ifndef HOTEND_OFFSET_Y
     #define HOTEND_OFFSET_Y { 0 } // Y offsets for each extruder
   #endif
-  #if HAS_HOTEND_OFFSET_Z && !defined(HOTEND_OFFSET_Z)
-    #define HOTEND_OFFSET_Z { 0 }
+  #ifndef HOTEND_OFFSET_Z
+    #define HOTEND_OFFSET_Z { 0 } // Z offsets for each extruder
   #endif
 #endif
 
diff --git a/Marlin/src/module/configuration_store.cpp b/Marlin/src/module/configuration_store.cpp
index 092934a66..83cb3b4c4 100644
--- a/Marlin/src/module/configuration_store.cpp
+++ b/Marlin/src/module/configuration_store.cpp
@@ -126,7 +126,7 @@ typedef struct SettingsDataStruct {
 
   float home_offset[XYZ];                               // M206 XYZ
 
-  #if HOTENDS > 1
+  #if HAS_HOTEND_OFFSET
     float hotend_offset[XYZ][HOTENDS - 1];              // M218 XYZ
   #endif
 
@@ -433,7 +433,7 @@ void MarlinSettings::postprocess() {
     #endif
     EEPROM_WRITE(home_offset);
 
-    #if HOTENDS > 1
+    #if HAS_HOTEND_OFFSET
       // Skip hotend 0 which must be 0
       for (uint8_t e = 1; e < HOTENDS; e++)
         LOOP_XYZ(i) EEPROM_WRITE(hotend_offset[i][e]);
@@ -1038,7 +1038,7 @@ void MarlinSettings::postprocess() {
       // Hotend Offsets, if any
       //
 
-      #if HOTENDS > 1
+      #if HAS_HOTEND_OFFSET
         // Skip hotend 0 which must be 0
         for (uint8_t e = 1; e < HOTENDS; e++)
           LOOP_XYZ(i) EEPROM_READ(hotend_offset[i][e]);
@@ -1749,16 +1749,8 @@ void MarlinSettings::reset(PORTARG_SOLO) {
     ZERO(home_offset);
   #endif
 
-  #if HOTENDS > 1
-    constexpr float tmp4[XYZ][HOTENDS] = {
-      HOTEND_OFFSET_X,
-      HOTEND_OFFSET_Y
-      #ifdef HOTEND_OFFSET_Z
-        , HOTEND_OFFSET_Z
-      #else
-        , { 0 }
-      #endif
-    };
+  #if HAS_HOTEND_OFFSET
+    constexpr float tmp4[XYZ][HOTENDS] = { HOTEND_OFFSET_X, HOTEND_OFFSET_Y, HOTEND_OFFSET_Z };
     static_assert(
       tmp4[X_AXIS][0] == 0 && tmp4[Y_AXIS][0] == 0 && tmp4[Z_AXIS][0] == 0,
       "Offsets for the first hotend must be 0.0."
@@ -2163,7 +2155,7 @@ void MarlinSettings::reset(PORTARG_SOLO) {
       SERIAL_ECHOLNPAIR_P(port, " Z", LINEAR_UNIT(home_offset[Z_AXIS]));
     #endif
 
-    #if HOTENDS > 1
+    #if HAS_HOTEND_OFFSET
       if (!forReplay) {
         CONFIG_ECHO_START;
         SERIAL_ECHOLNPGM_P(port, "Hotend offsets:");
@@ -2173,9 +2165,7 @@ void MarlinSettings::reset(PORTARG_SOLO) {
         SERIAL_ECHOPAIR_P(port, "  M218 T", (int)e);
         SERIAL_ECHOPAIR_P(port, " X", LINEAR_UNIT(hotend_offset[X_AXIS][e]));
         SERIAL_ECHOPAIR_P(port, " Y", LINEAR_UNIT(hotend_offset[Y_AXIS][e]));
-        #if HAS_HOTEND_OFFSET_Z
-          SERIAL_ECHOPAIR_P(port, " Z", LINEAR_UNIT(hotend_offset[Z_AXIS][e]));
-        #endif
+        SERIAL_ECHOPAIR_P(port, " Z", LINEAR_UNIT(hotend_offset[Z_AXIS][e]));
         SERIAL_EOL_P(port);
       }
     #endif
diff --git a/Marlin/src/module/delta.cpp b/Marlin/src/module/delta.cpp
index 308eed106..ba4c018f9 100644
--- a/Marlin/src/module/delta.cpp
+++ b/Marlin/src/module/delta.cpp
@@ -102,7 +102,7 @@ void recalc_delta_settings() {
   }while(0)
 
 void inverse_kinematics(const float raw[XYZ]) {
-  #if HOTENDS > 1
+  #if HAS_HOTEND_OFFSET
     // Delta hotend offsets must be applied in Cartesian space with no "spoofing"
     const float pos[XYZ] = {
       raw[X_AXIS] - hotend_offset[X_AXIS][active_extruder],
diff --git a/Marlin/src/module/motion.cpp b/Marlin/src/module/motion.cpp
index 864d04609..fbc211117 100644
--- a/Marlin/src/module/motion.cpp
+++ b/Marlin/src/module/motion.cpp
@@ -92,7 +92,7 @@ float destination[XYZE] = { 0 };
 uint8_t active_extruder; // = 0;
 
 // Extruder offsets
-#if HOTENDS > 1
+#if HAS_HOTEND_OFFSET
   float hotend_offset[XYZ][HOTENDS]; // Initialized by settings.load()
 #endif
 
diff --git a/Marlin/src/module/motion.h b/Marlin/src/module/motion.h
index 6850250b6..51e047892 100644
--- a/Marlin/src/module/motion.h
+++ b/Marlin/src/module/motion.h
@@ -78,7 +78,7 @@ extern int16_t feedrate_percentage;
 
 extern uint8_t active_extruder;
 
-#if HOTENDS > 1
+#if HAS_HOTEND_OFFSET
   extern float hotend_offset[XYZ][HOTENDS];
 #endif